They were later signed their second record deal and went on to release their second studio album Every Six Seconds. Saliva later released their third studio album titled Back into Your System on November 12, 2002 which reached No. 19 on the Billboard 200. Back into Your System launched one of Saliva's most successful songs, "Always", reaching No. 51 on the Billboard Hot 100 and No. 1 on the Modern Rock Chart. Three years after Survival of the Sickest, Saliva released Blood Stained Love Story on January 23, 2007, repeating Back into Your System's chart performance at No. 19 on the Billboard 200. Its first single, "Ladies and Gentlemen", peaked at No. 2 on the Mainstream Rock Chart.
Saliva was originally founded in Memphis, Tennessee in September 1996. After competing in the National Academy of Recording Arts & Sciences Grammy Showcase competition, where they advanced to the final round in New York City, the group self-released their self-titled debut album which sold over 10,000 copies in their region, prompting record labels to take notice.
In early January 2012 it was announced that Bobby Amaru has joined Saliva as the new vocalist. According to Wayne, ”he is a 28 year old singer, songwriter, producer from Jacksonville, Florida who has a GREAT voice and will not only bring some fresh blood into the band but; will also put a new spin on the Saliva sound.” Amaru was the front man of his solo band Amaru, as well as the drummer for Burn Season. On the 30th of November, it was announced that the band had just signed a new record deal with Rum Bum Records & that after they have finished their current tour, the band will return home to finish writing the new album and begin recording in January for a release date some time in the summer.